TRIFUNCTIONAL ANTIBODY-CYTOKINE FUSION PROTEIN FORMATS FOR TUMOR-TARGETED COMBINATION OF IL-15 WITH IL-7 OR IL-21

Trifunctional antibody-cytokine fusion protein formats for tumor-targeted combination of IL-15 with IL-7 or IL-21

Cytokines from the common gamma chain receptor family, such as IL-15, IL-21 and IL-7, show promise for cancer immunotherapy and have been incorporated individually into the immunocytokine approach.However, their efficacy as monotherapy is limited.Here, we investigated the molecular design of tumor-directed trifunctional antibody-cytokine fusion pro

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Effect of Memo®, a natural formula combination, on Mini-Mental State Examination scores in patients with mild cognitive impairment

Mostafa Yakoot,1 Amel Salem,2 Sherine Helmy3 1Green Clinic and Research Center, 2Mabarrah Clinics, 3Pharco Pharmaceutical Industries, Alexandria, Egypt Background: Mild cognitive impairment encompasses the clinical continuum between physiologic age-related cognitive changes and dementia.A variety of medications, including herbal preparations (in pa

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